1- (2′-Deoxy-2′-fluoro- β-D-arabinofuranosyl)uracil

Category:

ArtikelNr.

MBCB001012

CAS Nr.

69123-94-0

Name

1- (2′-Deoxy-2′-fluoro- β-D-arabinofuranosyl)uracil

Description

Antineoplastic prodrug

Specification规格 (g)

100

Chemical Formula:

C9H11FN2O5

Molecular Weight:

246.2 g/mol

Hazards identification

  • Health Hazards

acute toxicity (Category 4)

acute toxicity (Category 4)

Skin corrosion/irritation (Category 2)

Serious eye damage/eye irritation (Category 2)

acute toxicity (Category 4)

Germ cell mutagenicity 1B

Single exposure: Respiratory tract irritation (Category 3)

  • Enviromental Hazards

not classified

  • Physical Hazards

not classified

GHS Labeling

  • Symbol

GHS07 exclamation mark

  • Pictogram

GHS08 health hazard

  • Pictogram

 

  • Signal Word

Danger Danger

  • Hazard Statement

H302 Harmful if swallowed.

H312 Harmful in contact with skin.

H332 Harmful if inhaled.

H315 Causes skin irritation.

H319 Causes serious eye irritation.

H335 May cause respiratory irritation.

H340 May cause genetic defects.

 

  • Precautionary Statement

P270 Do no eat, drink or smoke when using this product.

P280 Wear protective gloves/protective clothing/eye protection/face protection.

P301 IF SWALLOWED:

P312 Call a POISON CENTER or doctor/physician if you feel unwell.

P304 IF INHALED:

P340 Remove casualty to fresh air and keep at rest inaposition comfortable for breathing. P305 IF IN EYES:

P351 Rinse cautiously with water for several minutes.

P338 Remove contact lenses, if present and easy to do.Continue rinsing.

P403 Store in a well-ventilated place.

P233 Keep container tightly closed.

P501 Dispose of contents / container in accordance with local / regional / national /

international regulations.

 

First aid measures

  • First Aid: Eye

Immediately flush eyes with plenty of flowing water for 10 to 15 minutes holding eyelids apart. Consult an ophthalmologist.

  • First Aid: Skin

Wash immediately with plenty of water and soap for at least 15 minutes. Remove contaminated clothing and shoes. Wash contaminated clothes before reuse. Call a physician.

  • First Aid: Ingestion

Wash out mouth with water provided person is conscious. Call a physician.

  • First Aid: Inhalation

Remove casualty to fresh air and keep warm and at rest. If breathing is irregular or stopped, administer artificial respiration. Call a physician.

  • Hints for Physician: Treatment

Treat symptomatically.

 

Accidental release measures

  • Personal Precautions

Wear breathing apparatus if exposed to vapours/dusts/aerosols. Provide adequate ventilation.

  • Environmental Precautions

Do not allow to enter into soil/subsoil. Do not allow to enter into surface water or drains. Ensure all waste water is collected and treated via a waste water treatment plant.

  • Methods for Cleaning or Taking Up

not available

  • Further Accidental Release Measures

Collect in closed and suitable containers for disposal. Clear contaminated areas thoroughly. Ventilate affected area.

 

Handling advice

Avoid contact with skin, eyes and clothing. Avoid ingestion and inhalation. Avoid prolonged or repeated exposure. Remove contaminated clothing and wash before reuse. Wash thoroughly after handling.

 

Storage

  • Storage temperature

store at 2°C – 8°C

  • Storage Requirements

Keep away from incompatible substances. Keep container tightly closed when not in use.

 

Personal Protective Equipment

  • Respiratory Protection

Wear NIOSH/MSHA or European Standard EN 149 approved respirator.

  • Hand Protection

Wear compatible chemical-resistant gloves to prevent skin exposure.

  • Eye Protection

Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA.

  • Body Protection

Wear compatible chemical-resistant gloves and clothing to prevent skin exposure.

  • Advice on Safe Handling

Wash contaminated clothing before reuse. Wear appropriate protective clothing to prevent exposure.

 

Physical and chemical properties

  • Color

white

  • Form

Powder

 

Stability and reactivity

  • Conditions to Avoid

incompatible materials

  • Substances to Avoid

strong oxidizers

  • Decomposition Products

nitrogen oxides (NOx), carbon dioxide (CO2), hydrogen fluoride, carbon monoxide

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