2′-Deoxycytidine

CAS: 207121-53-7

Artikel Nr: A6201

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Category:

Properties

CAS: 207121-53-7

MF: C9H15N3O5

MW: 245.24

EINECS: 213-454-1

MDL No: MFCD00006547

Melting point: 209-211 °C(lit.)

Storage temp: Keep in dark place, Sealed in dry,2-8°C

Solubility: Methanol (Slightly), Water (Slightly)

Form: Solid

Color: White

Stability: Hygroscopic

 

Safety

Chemical Safety:

Signal word: Warning

Hazard statements: H302-H315-H319-H335

Precautionary statements: P261-P305+P351+P338

WGK Germany: 3

RTECS: HA3800000

F: 10

 

Uses

A deoxyribonucleoside as Eg5 kinesin modulator with antiproliferative and apoptosis-inducing activity.

 

Purification Methods

Purify 2′-deoxycytidine by recrystallisation from MeOH/Et2O or EtOH and dry it in air. [NMR: Miles J Am Chem Soc 85 1007 1963, UV: Fox & Shugar Biochim Biophys Acta 9 369 1952.] The hydrochloride crystallises from H2O/EtOH and has m 174o(dec, 169-173o). [Walker & Butler Can J Chem 34 1168 1956.] The picrate has m 208o(dec). [Fox et al. J Am Chem Soc 83 4066 1961, Beilstein 25 III/IV 3662.]

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