4-Nitrophenyl beta-D-glucopyranosiduronic acid

CAS: 10344-94-2

Artikel Nr: B6006

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Category:

Properties

Synonyms:

4-NITROPHENYL-BETA-D-GLUCOPYRANOSIDURONIC ACID;

(4-NITRO)PHENYL-BETA-D-GLUCORONIDE;

4-NITROPHENYL-BETA-D-GLUCURONIC ACID;

4-NITROPHENYL-BETA-D-GLUCURONIDE;

P-NITROPHENYL BETA-D-GLUCOPYRANOSIDURONIC ACID;

P-NITROPHENYL BETA-D-GLUCURONIDE;

PNP-BETA-D-GLCA;

PNP BETA-D-GLUCURONIDE

CAS: 10344-94-2

MF: C12H13NO9

MW: 315.23

EINECS: 233-753-0

Product Categories: Biochemistry; Glucose; Substrates; Glycosides; Sugars; substrate; Carbohydrates & Derivatives; Glucuronides

Mol File: 10344-94-2.mol

Melting point: 93°C

Boiling point: 644.4±55.0 °C(Predicted)

density: 1.731±0.06 g/cm3(Predicted)

storage temp: -20°C

solubility: H2O: 0.1 g/mL, clear, faintly yellow

pka: 2.69±0.70(Predicted)

form: Liquid

color: Clear colorless to light yellow

optical activity: [α]20/D 102±3°, c = 1% in ethanol

BRN: 1438576

InChIKey: QSUILVWOWLUOEU-GOVZDWNOSA-N

 

Safety

Chemical Safety:

Safety Statements: 22-24/25

WGK Germany: 3

F: 10-21

Signal word: Warning

Hazard statements: H302-H315-H319-H335

Precautionary statements: P261-P305+P351+P338

 

Uses

4-Nitrophenyl β-D-glucuronide has been used as substrate in acetate buffer to measure β-glucuronidase.

4-Nitrophenyl β-D-glucuronide has been used for determining the β-glucuronidase activity in urine samples, β-glucuronidase activity of bacteria in caecum content digesta and bovine liver. It has also been used to study the inhibitory effect of Phyllanthus amarus extracts on β-glucuronidase.

 

Definition

ChEBI: A beta-D-glucosiduronic acid having a 4-nitrophenyl substituent at the anomeric position.

 

General Description

Chromogenic substrate for β-glucuronidase (Km = ~0.22 mM).

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