Telbivudine

Category:

ArtikelNr.

MBCB001010

CAS Nr.

3424-98-4

Name

Telbivudine

Description

L-Thymidine is an antiviral drug that is used in the treatment of chronic hepatitis. It has been shown to be active against a range of viruses, including HIV, HSV, and HBV. L-Thymidine can also be used to treat patients with cancer as an anti-cancer agent. L-Thymidine is a prodrug that is converted into thymidine triphosphate (TTP), which inhibits viral DNA polymerase by competitive inhibition. The antiviral activity of L-Thymidine may be due to its ability to inhibit the synthesis of viral proteins required for viral replication by interfering with the protein production process or by inhibiting the formation of dsDNA during reverse transcription.

Specification规格 (g)

100

Chemical Formula:

C10H14N2O5

Molecular Weight:

242.23 g/mol

Hazards identification

  • Health Hazards

acute toxicity (Category 4)

  • Enviromental Hazards

not classified

  • Physical Hazards

not classified

GHS Labeling

  • Symbol

GHS07 exclamation mark

  • Pictogram
  • Signal Word

Warning Warning

  • Hazard Statement

H302 Harmful if swallowed.

  • Precautionary Statement

P270 Do no eat, drink or smoke when using this product.

P301+P312 IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. P330 Rinse mouth.

P501 Dispose of contents / container in accordance with local / regional / national / international regulations.

 

First aid measures

  • First Aid: Eye

Immediately flush eyes with plenty of flowing water for 10 to 15 minutes holding eyelids apart. Consult an ophthalmologist.

  • First Aid: Skin

Wash immediately with plenty of water and soap for at least 15 minutes. Remove contaminated clothing and shoes. Wash contaminated clothes before reuse. Call a physician.

  • First Aid: Ingestion

Wash out mouth with water provided person is conscious. Call a physician.

  • First Aid: Inhalation

Remove casualty to fresh air and keep warm and at rest. If breathing is irregular or stopped, administer artificial respiration. Call a physician.

  • Hints for Physician: Treatment

Treat symptomatically.

 

Accidental release measures

  • Personal Precautions

Wear breathing apparatus if exposed to vapours/dusts/aerosols. Provide adequate ventilation.

  • Environmental Precautions

Do not allow to enter into soil/subsoil. Do not allow to enter into surface water or drains. Ensure all waste water is collected and treated via a waste water treatment plant.

  • Methods for Cleaning or Taking Up

not available

  • Further Accidental Release Measures

Collect in closed and suitable containers for disposal. Clear contaminated areas thoroughly. Ventilate affected area.

 

Handling advice

Avoid contact with skin, eyes and clothing. Avoid ingestion and inhalation. Avoid prolonged or repeated exposure. Remove contaminated clothing and wash before reuse. Wash thoroughly after handling.

 

Storage

  • Storage temperature

store at 2°C – 8°C

  • Storage condition

close container well

  • Storage Requirements

Keep away from incompatible substances. Keep container tightly closed when not in use.

 

Personal Protective Equipment

  • Respiratory Protection

Wear NIOSH/MSHA or European Standard EN 149 approved respirator.

  • Hand Protection

Wear compatible chemical-resistant gloves to prevent skin exposure.

  • Eye Protection

Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA.

  • Body Protection

Wear compatible chemical-resistant gloves and clothing to prevent skin exposure.

  • Advice on Safe Handling

Wash contaminated clothing before reuse. Wear appropriate protective clothing to prevent exposure.

 

Physical and chemical properties

  • Color

white

  • Form

powder

  • Phase Transition Solid/Liquid

188 °C

 

Stability and reactivity

  • Conditions to Avoid

incompatible materials

  • Substances to Avoid

strong oxidizers

  • Decomposition Products

nitrogen oxides (NOx), carbon dioxide (CO2), carbon monoxide

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