mRNex® Deoxyribonuclease I (DNase I) GMP-grade (2 U/μL)
Recombinant DNase I for removing DNA templates from RNA preparations and other DNA-digestion workflows.
Broad DNA substrates
GMP-process manufacture
RUO
Product overview
mRNex® Deoxyribonuclease I (DNase I) GMP-grade (2 U/μL). Recombinant DNase I for removing DNA templates from RNA preparations and other DNA-digestion workflows.
IVT template removal
Digests DNA remaining after in-vitro transcription.
Broad DNA substrates
Acts on single- and double-stranded DNA, including chromatin.
GMP-process manufacture
The handbook states manufacture in accordance with GMP process requirements.
Specifications
| Parameter | Value |
|---|---|
| Activity concentration | 2 U/µL |
| Optimum temperature | 37°C |
| Source | Recombinant E. coli |
| Format | Liquid |
| Storage | −25 to −15°C, 1 year; dry-ice shipment. |
| Intended use | Research use only |
Pack sizes & ordering
| Catalog No. | Pack size |
|---|---|
| LD10611 | 500 U |
| LD10611 | 2,000 U |
| LD10611 | 10,000 U |
The handbook lists both 10,000 U and 10 KU; these equivalent quantities are shown once. Source: LD10611_mRNex® Deoxyribonuclease I (DNase I) GMP-grade (2 U-μL)_10611ES.pdf, pp. 2–3.
Performance & validation
Digests DNA remaining after in-vitro transcription. Acts on single- and double-stranded DNA, including chromatin. The handbook states manufacture in accordance with GMP process requirements. Source: LD10611 handbook/CoA, pp. 2–3.
IVT template removal
Digests DNA remaining after in-vitro transcription.
Broad DNA substrates
Acts on single- and double-stranded DNA, including chromatin.
GMP-process manufacture
The handbook states manufacture in accordance with GMP process requirements.
Product documents
Product FAQs
Recombinant DNase I for removing DNA templates from RNA preparations and other DNA-digestion workflows. −25 to −15°C, 1 year; dry-ice shipment. No. It is for research use only.What is this product used for?
How should the product be stored?
Is this product intended for diagnostic or clinical use?