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NUCQX® N-96 Fully Automated Nucleic Acid Extractor

The N-96 Fully Automated Nucleic Acid Extraction Instrument is an integrated automated nucleic acid preparation system based on magnetic bead adsorption and transfer.

samples / run

96

20 - 40

minutes

3

modules

CE

IVDR

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Product overview

The NUCQX® N-96 is a fully automated, high-throughput nucleic acid extraction system based on magnetic bead technology. It purifies DNA/RNA from 1–96 samples per run – or, in the 24-well large-volume configuration, from 1–24 samples with working volumes of up to 10 mL – and handles whole blood, viruses, tissues, plants, bacteria and cultured cells. Sealed magnetic rods with disposable sleeves move the beads between reagent wells and mix by rapid up-and-down motion, taking every sample through lysis, binding, washing and elution without manual pipetting between steps. Programmable heating with active cooling of adjacent stations, a HEPA air filter and built-in UV sterilisation deliver reliable, reproducible results for downstream gene analysis and molecular research.

Key Features

Fully Automated Workflow

Lysis, binding, washing, and elution via sealed magnetic rod transfer — no pipetting between steps means no cross-contamination or aerosols.

96 Samples per Run

Process 1–96 samples in a single run, or switch to the 24-well large-volume configuration for working volumes up to 10 mL.

Programmable Touch-Screen Control

Pre-installed protocols plus full custom editing: mixing modes, 10 mixing speeds, times, volumes and temperatures. Searchable, password-protectable programme list.

Precise Temperature Control

Heating up to 120 °C at preset stations, while adjacent stations are actively cooled to prevent temperature crossover.

Built-in UV + HEPA Sterilisation

Post-run UV decontamination with door-interlock safety, plus HEPA filtration to keep the chamber contamination-free between runs

Power-Failure Protection

After a power cut, the N-96 remembers the run status and resumes from where it stopped.

Specifications

ParameterValue
ModelN-96 (96-well version; 24-well large-volume version available)
Throughput1–96 samples per run (24-well large-volume version: 1–24 samples)
Working volume20–1,000 µL (24-well large-volume version: 50–10,000 µL)
Extraction principleMagnetic bead adsorption with sealed magnetic rod and rod-sleeve transfer, no pipetting between steps
Sample typesWhole blood, viruses, tissues, plants, bacteria, cultured cells
Magnetic bead recovery rate>99%
Permanent magnetic rods4,000–6,000 Gs
Temperature rangeRoom temperature to 120 °C; adjacent stations actively cooled to prevent temperature crossover
MixingProgrammable mixing modes with 10 selectable mixing speeds
Display / UIColour touch screen, searchable programme list, real-time run display with countdown
ProgrammesPre-installed extraction protocols, custom programme editing, password-protected programmes
Contamination controlHEPA air filter, built-in UV lamp with user-set timer
Interior LED lightSwitchable during the run
Power-failure protectionInterrupted runs can be resumed after power is restored
Power supply110–230 V, 350 W, 50/60 Hz
Dimensions (L × W × H)87 × 45 × 50 cm
Operating environment10–40 °C, 30–80% relative humidity, altitude below 2,000 m
Warranty1 year
Intended useFor research use only. Not for use in diagnostic or clinical procedures.

Working Principle

NUCQX S-48 extraction workflow Five steps of magnetic-bead nucleic acid extraction: lysis, binding, magnetic transfer, washing and elution, with sealed magnetic rods moving the beads between wells. 1 Lysis Sample is lysed with vortex mixing and heat 2 Binding DNA/RNA binds to the magnetic beads lift 3 Magnetic transfer Sealed rods capture the beads and move them — no pipetting, ≥95% bead recovery 4 Washing Sequential washes remove inhibitors DNARNA 5 Elution Pure DNA/RNA eluted in 30–200 µL Load · Start · Walk away closed-system transfer · 20–40 min per run
NUCQX S-48 extraction workflow Five steps of magnetic-bead nucleic acid extraction: lysis, binding, magnetic transfer, washing and elution, with sealed magnetic rods moving the beads between wells. 1 Lysis Sample lysed with vortex mixing and heat 2 Binding DNA/RNA binds to magnetic beads 3 Magnetic transfer Sealed rods capture beads — no pipetting, ≥95% recovery 4 Washing Sequential washes remove inhibitors DNARNA 5 Elution Pure DNA/RNA in 30–200 µL Load · Start · Walk away — closed-system magnetic rod transfer between wells, 20–40 min per run

Product documents

Request EU Declaration of Conformity (CE-IVDR)Request ISO 13485 Certificate

Certifications & Compliance

CE-IVDR

EU Declaration of Conformity available on request.

ISO 13485

Manufactured under an ISO 13485 quality management system

GMP Manufacturer

Produced to Good Manufacturing Practice standards for consistent quality.

EU Import — Complete Docs

SHT Technology GmbH (Kronberg) handles all import compliance.

Bilingual Support

Manual and support available in German and English

Related Applications​

Clinical Diagnostics & IVD

Pathogen detection from respiratory, blood, and swab samples feeding RT-PCR and other IVD workflows.

Infectious Disease Testing

Viral and bacterial nucleic acid extraction — SARS-CoV-2, influenza, hepatitis, and emerging pathogen surveillance.

Molecular Biology Research

Genomic DNA and total RNA extraction for sequencing, gene expression, and functional assays

Pharmaceutical QC & R&D

High-throughput nucleic acid preparation for drug target identification and batch QC testing.

Biobank & Core Facilities

Automated, walk-away processing for biobank archives and cohort studies at scale.

Food Safety & Environment

GMO testing, food pathogen screening, and environmental monitoring from complex matrices.

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