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NUCQX® S-48 Nucleic Acid Extraction System

Fully automated magnetic bead extraction for 48 samples per run — three independent modules, 9-inch colour touch screen, built-in UV sterilisation, and a closed-system design that eliminates contamination risk. Walk-away processing from lysis to pure DNA/RNA in 20–40 minutes.

samples / run

48

20 - 40

minutes

3

modules

CE

IVDR

Request Quote

Product overview

The NUCQX® S-48 is a fully automated nucleic acid extraction system based on magnetic bead technology. Three independent processing modules and a 9-inch colour touch screen deliver DNA/RNA extraction for 1–48 samples per run with minimal hands-on time. Sealed magnetic rods move the beads between wells, so there is no pipetting between steps — eliminating the contamination risk from liquid splashing and aerosols and ensuring reliable, reproducible results.

Key Features

Fully Automated Workflow

Lysis, binding, washing, and elution via sealed magnetic rod transfer — no pipetting between steps means no cross-contamination or aerosols.

Three Independent Modules

Run any multiple of 16 samples — 8, 16, 24, 32, or 48 — without wasting reagents. Modules select individually from the touch screen.

9-Inch Touch Screen

Stores ≥120 user-defined protocols, searchable by name. Real-time run display shows remaining time, step, and station.

Observation Window

In-chamber LED lets staff observe the mechanism through the transparent door without interrupting the run.

Built-in UV + HEPA Sterilisation

Post-run UV decontamination with door-interlock safety, plus HEPA filtration to keep the chamber contamination-free between runs

Two Colour Options

Available in black (ABS alcohol-resistant paint) or white (metal chassis, matte powder coating)

Specifications

ParameterValue
ModelS-48 (MBINS048001)
Throughput1–48 samples per run (3 independent modules, up to 16 samples each)
Extraction principleMagnetic beads with sealed magnetic rod transfer, no cross-well pipetting
Sample typesWhole blood, serum, plasma, throat/nasal swabs, tissue, urine, faeces, exfoliated cells, puncture fluid
Sample input volume50–2000 µL
Elution volume30–200 µL
Extraction time20–40 min per run (protocol-dependent)
Temperature rangeRoom temperature to 125 °C (adjustable per step)
Mixing modeOmnidirectional vortex liquid mixing
Bead recovery rate≥95%
Display / UI9-inch colour touch screen, searchable programme list, real-time run display
Programme storage≥120 user-defined protocols
UV sterilisationBuilt-in UV lamp, user-set timer, door-interlock safety
Contamination controlClosed-system magnetic rod transfer, no pipetting between steps, aerosol prevention
Interior LED lightSwitchable in-run LED for observation through the transparent chamber door
Power supplyAC 220 V ±10%, 50/60 Hz
Regulatory statusCE-IVDR; EU Declaration of Conformity available
Compatible reagent kitsNUCQX® magnetic bead nucleic acid extraction kits (genomic DNA, total RNA, viral nucleic acids)

Working Principle

NUCQX S-48 extraction workflow Five steps of magnetic-bead nucleic acid extraction: lysis, binding, magnetic transfer, washing and elution, with sealed magnetic rods moving the beads between wells. 1 Lysis Sample is lysed with vortex mixing and heat 2 Binding DNA/RNA binds to the magnetic beads lift 3 Magnetic transfer Sealed rods capture the beads and move them — no pipetting, ≥95% bead recovery 4 Washing Sequential washes remove inhibitors DNARNA 5 Elution Pure DNA/RNA eluted in 30–200 µL Load · Start · Walk away closed-system transfer · 20–40 min per run
NUCQX S-48 extraction workflow Five steps of magnetic-bead nucleic acid extraction: lysis, binding, magnetic transfer, washing and elution, with sealed magnetic rods moving the beads between wells. 1 Lysis Sample lysed with vortex mixing and heat 2 Binding DNA/RNA binds to magnetic beads 3 Magnetic transfer Sealed rods capture beads — no pipetting, ≥95% recovery 4 Washing Sequential washes remove inhibitors DNARNA 5 Elution Pure DNA/RNA in 30–200 µL Load · Start · Walk away — closed-system magnetic rod transfer between wells, 20–40 min per run

Product documents

Request EU Declaration of Conformity (CE-IVDR)Request ISO 13485 Certificate

Certifications & Compliance

CE-IVDR

EU Declaration of Conformity available on request.

ISO 13485

Manufactured under an ISO 13485 quality management system

GMP Manufacturer

Produced to Good Manufacturing Practice standards for consistent quality.

EU Import — Complete Docs

SHT Technology GmbH (Kronberg) handles all import compliance.

Bilingual Support

Manual and support available in German and English

Related Applications​

Clinical Diagnostics & IVD

Pathogen detection from respiratory, blood, and swab samples feeding RT-PCR and other IVD workflows.

Infectious Disease Testing

Viral and bacterial nucleic acid extraction — SARS-CoV-2, influenza, hepatitis, and emerging pathogen surveillance.

Molecular Biology Research

Genomic DNA and total RNA extraction for sequencing, gene expression, and functional assays

Pharmaceutical QC & R&D

High-throughput nucleic acid preparation for drug target identification and batch QC testing.

Biobank & Core Facilities

Automated, walk-away processing for biobank archives and cohort studies at scale.

Food Safety & Environment

GMO testing, food pathogen screening, and environmental monitoring from complex matrices.

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